Synthesis, Anti-Bacterial and Anti-Fungal Evaluation of Pyrazoline Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis, Anti-bacterial and Anti-fungal evaluation of 3-(Substitutedphenyl)-N-(4H-1,2,4-triazol-4 yl)acrylamide
The Series of 3-(Substitutedphenyl)-N-(4H-1,2,4-triazol-4-yl)acrylamide compounds were prepared byreaction of 4-amino-1,2,4-Triazole with Acetyl Chloride followed by Claisen-Schmidt Condensation reactionwith different aromatic aldehydes. The structures of new compounds were confirmed by IR, 1H-NMR and13C-NMR spectral data. Anti-bacterial and Anti-fungal activities were evaluated and compared wi...
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In the present investigation, a series of 4-(4-(dimethylamino) benzyl)-3-methyl-1Hpyrazol-5(4H)-one analogues of pyrazole were synthesized by cyclization of mannich base with hydrazine hydrate. The nitrogen functionality of 4-(4-(dimethylamino) benzyl)-3-methyl-1Hpyrazol-5(4H)-one was alkylated with different halogenated alkylated substituted chain in the presence of base. The chemical structur...
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A new series of 2-(5-nitro-2-heteroaryl)-1,3,4-thiadiazole derivatives, including nitro furan, nitro thiophene and nitro imidazole, were synthesized and screened in vitro for their inhibitory activity against eight bacterial strains. The results showed that most of the synthesized compounds were active against Gram-positive bacteria, determined by MIC method. Among them, compounds <str...
متن کاملsynthesis, anti-bacterial and anti-fungal evaluation of 3-(substitutedphenyl)-n-(4h-1,2,4-triazol-4 yl)acrylamide
the series of 3-(substitutedphenyl)-n-(4h-1,2,4-triazol-4-yl)acrylamide compounds were prepared byreaction of 4-amino-1,2,4-triazole with acetyl chloride followed by claisen-schmidt condensation reactionwith different aromatic aldehydes. the structures of new compounds were confirmed by ir, 1h-nmr and13c-nmr spectral data. anti-bacterial and anti-fungal activities were evaluated and compared wi...
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ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2012
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2012/458035